Dedicated to static and dynamic condensed matter chemistry and materials science.

Advanced Crystallography

Uses a "rapid setup" crystallography facility that allows us to rapidly switch operation to the single-crystal instrument.

Liquid Surface/Interface X-ray Scattering

Used to investigate dynamical and structural properties of surfaces and interfaces in a variety of liquid and solid systems.

Anomalous Small Angle X-ray Scattering (ASAXS)

Focuses on element specific structural study of soft-matter in nano-dimensions.

Update on Status at NSF’s ChemMatCARS, September 20, 2021

Dear NSF’s ChemMatCARS Users,


Starting September 20, 2021, all general users and visitors to Argonne facilities, who are not Argonne employees or Collaborative Access Team (CAT) operations staff, will be required to report to the Argonne Information Center (AIC).

Before site access is granted, general users and visitors must:

  • attest to their vaccination status (form will be provided at the AIC)
  • if not fully vaccinated, show proof of a negative COVID-19 test result that is less than 72 hours old.

Given the current state of the COVID-19 pandemic, the APS user program is currently operational to support:

  • Mail-in/remote operation/participation for many capabilities. Remote and mail-in experimental access remain a priority.
  • Non-Argonne user presence, permitted ONLY for experiments that have gone through a pre-approval process based on need for site access, and requiring approval of the APS Director and that have met time-sensitive and mission-essential criteria.
  • An onsite user must have ANL site access, complete all APS required training courses and complete the on-site user request form. Contact apsuser@anl.gov for more information.
  • Non-Argonne users external to the APS should be prepared to show proof of vaccination to the beamline Point of Contact (POC) as identified on an Experiment Safety Assessment Form (ESAF) to take advantage of fully vaccinated privileges while onsite at the APS.
  • Site access credentials and a corresponding prox card will be issued to named onsite users on an approved ESAF and will be valid only for the facility-approved experiment duration.
  • Based on the most recent CDC guidance, all individuals regardless of vaccination status are required to wear masks and maintain six-foot social distancing while on site.

Please get in touch with the beamline contact to determine the ability of a specific beamline to support your research.

Please see the announcement on the APS home page or the User Info During the COVID Pandemic page.

Beamline scientist contacts: Dr. Yu-Sheng Chen, Dr. Wei Bu and Dr. Mrinal Bera.

Our Mission

NSF’s ChemMatCARS operates three experimental stations in the areas of advanced small-molecule crystallography, liquid surface and interface scattering, and small to wide-angle scattering at the Advanced Photon Source (APS), the premier undulator-based synchrotron source of high-brilliance high-energy x-rays in the U.S.A. The instrumentation at NSF’s ChemMatCARS provides information that addresses a broad range of issues in chemistry and materials research. NSF’s ChemMatCARS is supported by the Divisions of Chemistry (CHE) and Materials Research (DMR), National Science Foundation, under grant number NSF/CHE-1834750. Construction of a second beamline at NSF’s ChemMatCARS is supported by NSF grant CHE-1836674 with contributions from the Office of Multidisciplinary Activities within the Directorate of Mathematical and Physical Sciences and NSF Divisions in Chemistry (CHE), Molecular and Cellular Biology (MCB), and Chemical, Bioengineering, Environmental, and Transport Systems Engineering (CBET).

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Upcoming Events

11:00 am PME Distinguished Colloquium
PME Distinguished Colloquium
Nov 3 @ 11:00 am – 12:00 pm
Speaker: David Hsieh (Professor, Department of Physics, California Institute of Technology) Title: TBD Abstract: TBD    
10:00 am Soft Matter Interest Group Semin...
Soft Matter Interest Group Semin...
Nov 8 @ 10:00 am – 11:00 am
SPEAKER: Charles Maldarelli (Professor, Department of Chemical Engineering, The City College of New York ) TITLE: TBD LINK: https://uchicago.zoom.us/j/94220080385?pwd=b0VpcUFUOFNDT0pITk5WeTg4YjAwZz09 Meeting ID: 942 2008 0385 Password: 013444
11:00 am PME Distinguished Colloquium
PME Distinguished Colloquium
Dec 8 @ 11:00 am – 12:00 pm
Speaker: Eric Stefan Garrido Shaqfeh (Professor, Departments of Chemical Engineering and Mechanical Engineering, and the Institute for Computational and Mathematical Engineering, Stanford University) Title: TBD Abstract: TBD    
11:00 am PME Distinguished Colloquium
PME Distinguished Colloquium
Jan 12 @ 11:00 am – 12:00 pm
Speaker: Peter Zoller (Professor of Theoretical Physics, University of Innsbruck) Title: TBD Abstract: TBD    

Recent Publications

Ankit D. Kanthe, Raymond S. Tu et al., “No ordinary proteins: Adsorption and molecular orientation of monoclonal antibodiesScience Advances, 7(35), eabg2873 (2021)

Adam J. Rieth, Daniel G. Nocera et al., “How Radical Are “Radical” Photocatalysts? A Closed-Shell Meisenheimer Complex Is Identified as a Super-Reducing PhotoreagentJournal of the American Chemical Society, 143(35), 14352-14359 (2021)

Kate A. Jesse, John S. Anderson et al., “Iron(II) Complexes Featuring a Redox-Active Dihydrazonopyrrole Ligand.Z. Anorg. Allg. Chem. (Journal of Inorganic and General Chemistry), 647(14), 1415-1420 (2021)

Srikanth Nayak, Ahmet Uysal et al., “Origins of Clustering of Metalate–Extractant Complexes in Liquid–Liquid Extraction.ACS Appl. Mater. Interfaces, 13(20), 24194–24206 (2021)

Science Highlights

Visit our Science Highlights page for a full listing of highlights from NSF’s ChemMatCARS.

Advanced Crystallography

Liquid Surface/Interface X-ray Scattering

Anomalous Small Angle X-ray Scattering (ASAXS)

Latest News

Partnerships for Research and Education in Chemistry (PREC) with NSF’s ChemMatCARS (Click here)

NSF’s ChemMatCARS is seeking candidates to form partnerships for research and education in chemistry, in response to the solicitation for Partnerships for Research and Education in Chemistry (PREC), released on September 15, 2021, from the Division of Chemistry (CHE), NSF (https://beta.nsf.gov/funding/opportunities/partnerships-research-and-education-chemistry-prec). The PREC program will fund partnerships between minority-serving institutions (MSIs) and CHE-supported research centers/facilities, such as NSF’s ChemMatCARS.

2021 Neutron X-ray School

2021 Neutron X-ray School

ChemMatCARS beamline scientist Mrinal Bera hosted graduate students at the virtual NX School on July 22, 2021.