Dedicated to static and dynamic condensed matter chemistry and materials science.

Advanced Crystallography

Uses a "rapid setup" crystallography facility that allows us to rapidly switch operation to the single-crystal instrument.

Liquid Surface/Interface X-ray Scattering

Used to investigate dynamical and structural properties of surfaces and interfaces in a variety of liquid and solid systems.

Anomalous Small Angle X-ray Scattering (ASAXS)

Focuses on element specific structural study of soft-matter in nano-dimensions.

REAL ID Implementation for Access to Argonne

Dear NSF’s ChemMatCARS Users,


Starting Wednesday, May 3, 2023, site access credentials used to enter Argonne property must be REAL ID compliant. Persons without a REAL ID license will be required to provide other forms of identification before site access can be granted. Details on compliant documents can be found here.

This requirement applies to all non-employees, 18 years of age or older including facility users, resident users, visitors, vendors, etc.

Resident staff who have not yet provided REAL ID compliant ID/documents, will be contacted by Security. Long-term badges will not be issued past May 3 without submission of REAL ID documentation. Resident staff can reach out directly to the AIC for information on the REAL ID status.


QUESTIONS should be sent to heysecurity@anl.gov.


Our Mission

NSF’s ChemMatCARS operates three experimental stations in the areas of advanced small-molecule crystallography, liquid surface and interface scattering, and small to wide-angle scattering at the Advanced Photon Source (APS), the premier undulator-based synchrotron source of high-brilliance high-energy x-rays in the U.S.A. The instrumentation at NSF’s ChemMatCARS provides information that addresses a broad range of issues in chemistry and materials research. NSF’s ChemMatCARS is supported by the Divisions of Chemistry (CHE) and Materials Research (DMR), National Science Foundation, under grant number NSF/CHE-1834750 (click here for detail). Construction of a second beamline at NSF’s ChemMatCARS is supported by NSF grant CHE-1836674 with contributions from the Office of Multidisciplinary Activities within the Directorate of Mathematical and Physical Sciences and NSF Divisions in Chemistry (CHE), Molecular and Cellular Biology (MCB), and Chemical, Bioengineering, Environmental, and Transport Systems Engineering (CBET) (click here for detail).

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Upcoming Events

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Recent Publications

Advanced Crystallography

Zheng Zhou and Marina A. Petrukhina, “Planar, curved and twisted molecular nanographenes: Reduction-induced alkali metal coordinationCoordination Chemistry Reviews, 486, 215144 (2023)

Liquid Surface/Interface X-ray Scattering

Srikanth Nayak, Ahmet Uysal et al., “Elucidating Trivalent Ion Adsorption at Floating Carboxylic Acid Monolayers: Charge Reversal or Water Reorganization?J. Phys Chem Lett., 14(15), 3685-3690 (2023)

Anomalous Small Angle X-ray Scattering (ASAXS)

Rohan Murty and Krista S. Walton et al., “Interrogating Encapsulated Protein Structure within Metal-Organic Frameworks at Elevated TemperatureJ. A. Chem. Soc., 145(13), 7323-7330 (2023)

Science Highlights

Visit our Science Highlights page for a full listing of highlights from NSF’s ChemMatCARS.

Advanced Crystallography

Liquid Surface/Interface X-ray Scattering

Anomalous Small Angle X-ray Scattering (ASAXS)

Latest News

We Welcome Your Ideas about New Initiatives

New initiatives in biomembrane science and serial crystallography of small molecules, among others, will be developed at our new beamline. We are currently preparing a proposal to NSF for operations of these initiatives.  We welcome brief descriptions of how these...

Job Opportunity: Beamline Technician

Beamline Technician Position at Chemistry and Material Sciences Center for Advanced Radiation Sources (ChemMatCARS), University of Chicago ChemMatCARS, affiliated with the Pritzker School of Molecular Engineering (PME), the University of Chicago and funded by NSF, is...