We report a topology-guided, precise insertion of three distinct secondary linkers into a zirconium-based metal–organic framework, NPF-300. Constructed from a tetratopic linker L and Zr6 cluster, NPP-300 exhibits a unique scu topology and certain flexibility along the crystallographic a axis, and in conjunction with the conformation change of the primary ligand, is able to accommodate the stepwise insertion of three different secondary linkers along the a and c axes. Size-matching and mechanic strain of the resulting framework are two important factors that determine the chemical stability of the inserted linkers. Secondary linker insertion in NPF-300 significantly enables not only its porosity but also potentials to install up to three different functional groups for the construction of multivariate MOFs with homogeneity.
† Department of Chemistry, University of Nebraska—Lincoln, Lincoln, Nebraska 68588, United States
‡ ChemMatCARS, Center for Advanced Radiation Sources, The University of Chicago, 9700 South Cass Avenue, Argonne, Illinois 60439, United States
Adapted with permission from J. Am. Chem. Soc., 2018, 140(24), pp 7710-7715. Copyright 2018 American Chemical Society.